Drink plenty of fluids every day for the duration of your treatment with bortezomib, particularly when you vomit or have diarrhea.
elvitegravir/cobicistat/emtricitabine/tenofovir DF will increase amounts of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
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The therapeutic dose of bortezomib is individualized in Every client to stop overdose. Lethal outcomes occurred in human beings following the administration of a lot more than 2 times the proposed therapeutic dose of bortezomib. The indicators from overdose included the acute onset of symptomatic hypotension and thrombocytopenia. As there is absolutely no known antidote for bortezomib overdosage, monitoring of critical indicators and proper supportive care need to be initiated when drug overdosage is suspected.
iloperidone will increase levels of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Iloperidone is usually a time-dependent CYP3A Thalicarpine inhibitor and should lead to greater plasma levels of medication predominantly removed by CYP3A4.
voriconazole will improve the degree or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
There aren't any information on existence of bortezomib or metabolites in human milk, the results from the drug to the breast fed infant or on milk production
indinavir will enhance the stage or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
deferasirox will minimize the level or impact of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
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Talk to your health practitioner about consuming grapefruit and consuming grapefruit juice though utilizing this medication.
Bortezomib may make Crenolanib you extra likely to get bacterial infections or may make present infections even worse. Stay clear of anybody who has an infection which could conveniently distribute (such as chickenpox, COVID-19, measles, flu). Speak to your medical doctor In case you have been AXL-IN-13 exposed to an an infection or For additional information.